看见一个 Expert Review of Anticancer Therapy。你们前面用依维莫斯，血、肝肾功能还好。下一步是否考虑索拉非尼+依维莫斯。供你参考。
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Currently available feasibility data for possible combination strategies.
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Combination Feasibility according to preliminary data ( Z k9 c* Q7 x: p4 Q+ }0 N3 P
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9 S4 l% h+ }8 `2 eBevacizumab + sorafenib Yes, reduced dose
! |6 e z7 k8 U* Y" zBevacizumab + sunitinib† No
6 S* a0 @- J6 _5 L, TBevacizumab + temsirolimus Yes
! T% L+ ]+ e. X! }Bevacizumab + everolimus Yes
, c" ^( h5 s$ w- M* M, hSorafenib + sunitinib ? 5 e7 L( r/ O0 C% E- d8 U
Sorafenib + temsirolimus Yes, reduced dose 3 m7 j% i7 x3 x# F
Sorafenib + everolimus Yes, reduced dose V3 o* y' j4 w: c: F% o
Sunitinib + temsirolimus† No
5 n8 X2 A& W; e1 b/ [Sunitinib + everolimus ? / i* Z9 T4 g; }6 b- b4 y3 m
Temsirolimus + everolimus ? : E" z" Y! d. z$ N& J/ O
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, N$ ` T+ j+ [- V$ z# h* w†Led to US FDA warning.
) S: D5 | p! P Q/ W?: As yet unattempted combination.. b/ \1 S" W p# X, T0 ]2 B7 r
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